carbamazepine will reduce the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
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Dose adjustments of those medications together with other medicine which might be substrates for CYP2C19 could be important if modafinil is coadministered
The initial amount contains fourteen most important groups In accordance with anatomical web-site of motion, with therapeutic subgroups (second degree). The 3rd and fourth degrees are pharmacological and chemical subgroups, respectively, and the fifth degree would be the chemical compound itself.
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fosphenytoin will decrease the extent or impact of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
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modafinil will increase the stage or impact of diazepam intranasal by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Watch. Robust or average CYP2C19 inhibitors could minimize fee of diazepam elimination, thereby expanding adverse reactions to diazepam.
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cyclophosphamide will improve the stage or influence of modafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Not known.
Modafinil appeared to make a concentration-connected suppression of CYP2C9 exercise, consequently suggesting potential for CYP2C9 inhibition; caution if medicine that have a narrow therapeutic index